A comprehensive analysis of calreticulin mutants reveals distinct biophysicochemical proprieties with a potential for refined targeted therapies
Orhan Nedim Kurt, Mustafa Baran Ozturk, Eylul Civelek, Ilyas Chachoua
This study analyzes 76 CALR exon 9 variants to refine their classification based on charge architecture, revealing subgroups within Type-1-like variants and linking tail chemistry to receptor activation.
bioRxiv · Jun 24, 2026 · PreprintBioinformatics