Chemical screening of food-related chemicals for human fatty liver risk: Combining high content imaging of cellular responses with in vitro to in vivo extrapolation
F. A. Mueller, M. Stamou, F. Englert, O. Frenzel, S. Diedrich, J. F. Wambaugh, S. J. Sturla
This study combines high-content imaging and computational models to assess food-related chemicals' risk for fatty liver disease by extrapolating human oral equivalent doses from in vitro data.
bioRxiv · Jun 2, 2022Pharmacology & Toxicology