Molecular basis of EMRE-dependence of the human mitochondrial calcium uniporter
M. J. S. MacEwen, A. L. Markhard, M. Bozbeyoglu, F. Bradford, O. Goldberger, V. K. Mootha, Y. Sancak
The paper identifies an EMRE-dependence domain in human MCU that enables calcium conductance, revealing how EMRE stabilizes this domain for channel function.
bioRxiv · May 14, 2019 · PreprintBiochemistry