Author

F. De Sousa

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:imaging· 1

Frequent Co-Authors

B. Orr· 2 shared H. Maiato· 2 shared A. C. Figueiredo· 1 shared A. M. Gomes· 1 shared C. Ferras· 1 shared L. T. Ferreira· 1 shared M. Gomes· 1 shared M. Novais-Cruz· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 19 mutual co-author links

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2 shared papersCell Biology

B. Orr

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2 papers

Recent·Most cited

Misaligned chromosomes that satisfy the spindle assembly checkpoint are a strong predictor of micronuclei formation in dividing cancer cells

A. M. Gomes, B. Orr, M. Novais-Cruz, F. De Sousa, C. Ferras, H. Maiato

The paper shows that chronically misaligned chromosomes satisfying the SAC predict micronuclei formation in cancer cells but not in normal cells.

bioRxiv · Jul 20, 2022Cell Biology

An anaphase surveillance mechanism prevents micronuclei formation from mitotic errors

B. Orr, F. De Sousa, M. Gomes, L. T. Ferreira, A. C. Figueiredo, H. Maiato

This study identifies an Aurora B kinase-mediated mechanism that prevents micronuclei formation by integrating error correction with nuclear envelope reformation during anaphase.

bioRxiv · Feb 26, 2021Cell Biology