High-content analysis reveals senescence of cultured canine adipose-derived mesenchymal stromal cells to be reversible with a novel immortalization approach
A. Stojiljkovic, V. Gaschen, F. Forterre, U. Rytz, M. H. Stoffel, J. Bluteau
This study shows that senescence in canine adipose-derived mesenchymal stromal cells can be reversed using a novel PiggyBac Transposon System that expresses BMI1 and telomerase reverse transcriptase.
bioRxiv · Jul 27, 2020 · PreprintCell Biology