Globally defining the effects of mutations in a picornavirus capsid
F. Mattenberger, V. Latorre, O. Tirosh, A. Stern, R. Geller
The paper defines the effects of mutations in a picornavirus capsid by analyzing >90% of single amino acid mutations, identifying sequence determinants, and developing a bioinformatic approach to predict host protein targets.
bioRxiv · Oct 6, 2020Microbiology