Characterization of a selective, iron-chelating antifungal compound that disrupts fungal metabolism and synergizes with fluconazole
J. Corrales, L. Ramos-Alonso, J. Gonzalez-Sabin, N. Rios-Lombardia, N. Trevijano-Contador, H. Engen Berg, F. Sved Skottvoll, F. Moris, O. Zaragoza, P. Chymkowitch, I. Garcia, J. Enserink
This paper characterizes NR-6226C, a selective antifungal compound that chelates iron, disrupts fungal metabolism, and synergizes with fluconazole against Candida species.
bioRxiv · Aug 9, 2023Microbiology