Human prion proteins and mutants through the lens of systems biology
Swati Sharma, Faruque Siddique, Deep Nath, Jayanta Mukhopadhyay, Soumen Roy
The paper uses network analysis, MD simulations, and experiments to identify critical residues in human PrP that affect structural stability and misfolding.
bioRxiv · Oct 27, 2026 · PreprintSystems Biology