Molecular BiologybioRxivPreprint
Glycan-dependent two-step cell adhesion mechanism of Tc toxins
Daniel Roderer, Felix Bröcker, Oleg Sitsel…·Stefan Raunser
This study identifies two glycans, heparins/heparan sulfates and Lewis antigens, as receptors for Tc toxins, revealing a two-step adhesion mechanism involving glycan binding to toxin subunits.
DOI 10.1101/857730