Simple Causal Relationships in Gene Expression Discovered through Deep Learned Collective Variables
Ching-Hao Wang, Kalin Vetsigian, Chris Lin, Finnian Firth, Glyn Bradley, Lena Granovsky, Jeremy L. England
The paper develops a deep learning approach to identify simple causal relationships in gene expression by finding low-dimensional representations that predict genetic perturbation responses.
bioRxiv · Jan 18, 2023 · PreprintGenomics