Author

Florence Bugault

Inserm

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alice NevoneiD· 1 shared Caroline DemangeliD· 1 shared Chloé Veront· 1 shared Daniela RicciiD· 1 shared David HardyiD· 1 shared Irene VALCOZZENA· 1 shared Karen DruartiD· 1 shared Manon Capdeville· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

Alice NevoneORCID

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1 paper

Recent·Most cited

Targeting Sec61 to Silence Pathogenic Light-Chain Production in AL Amyloidosis

Daniela Ricci, Chloé Veront, Irene VALCOZZENA, Merlin Després, Alice Nevone, Marine Oberkampf, Mariette Matondo, Karen Druart, Thibaut Douché, Sarra Loulizi, David Hardy, Florence Bugault, Manon Capdeville, Mario Nuvolone, Caroline Demangel

This study targets the Sec61 translocon to suppress pathogenic light-chain production in AL amyloidosis, showing that mycolactone and synthetic inhibitors like A317 reduce LC secretion while highlighting the need for client selectivity.

bioRxiv · Sep 13, 2026 · PreprintCell Biology