The human-specific gene FRMPD2B couples postnatal experience to the expansion of cortical connectivity
Eirini Christopoulou, Joseph Zamith, Pauline Bonadonna, Mariana Rivero Romano, M. Vaudin, Wendy Nguyen, Clarisse Brunet, Corinne Blugeon, Sophie Lemoine, Francois Giudicelli, Alexandre D. Baffet, Cécile Charrier
This paper identifies the human-specific gene FRMPD2B as an activity- and experience-regulated modifier of cortical connectivity, showing its role in postnatal brain development.
bioRxiv · Nov 1, 2026 · PreprintNeuroscience