G. Berridge

Senescent tenocytes drive an age-associated loss of cell-extracellular matrix homeostasis, which can be partially restored using dihydroresveratrol

This study shows that senescent tenocytes contribute to age-related tendon degeneration and that dihydroresveratrol can partially restore matrix homeostasis.

SoftHybrid: A Hybrid Imputation Algorithm Optimised for Single-Cell Proteomics Data

SoftHybrid improves single-cell proteomics data imputation by jointly modeling missingness and protein abundance, outperforming existing methods at low input and matching them at the mini-bulk level.

Altered Hormone and Bioactive Lipid Plasma Profile in Rodent Models of Polycystic Ovarian Syndrome Revealed by Targeted Mass Spectrometry

This study identifies altered plasma lipid profiles in rodent PCOS models using targeted mass spectrometry, revealing both similarities and differences compared to human PCOS.

A resource for extracellular vesicles from activated CD4 T cells that relay pro-inflammatory signals

This study characterizes extracellular vesicles from activated CD4 T cells and shows their pro-inflammatory effects on antigen-presenting cells, providing a resource for EV-based therapeutic development.

Compartmentalisation proteomics revealed endolysosomal protein network changes in a goat model of atrial fibrillation

The paper uses proteomics and other methods to study endolysosomal changes in a goat model of atrial fibrillation, identifying upregulated pathways and specific proteins.

Cardiac Atrial Compartmentalisation Proteomics: A Modified Density Gradient Method to Analyse Endo-lysosomal Proteins

The paper presents a modified density gradient method for isolating endo-lysosomal proteins from cardiac tissue and reports proteomic analysis of these fractions in guinea pigs.