Author

G. Lorengo

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Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

A. Inga· 1 shared E. Biasini· 1 shared G. Spagnolli· 1 shared M. Rigoli· 1 shared P. Monti· 1 shared R. Potestio· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

6 top collaborators · 15 mutual co-author links

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1 shared paperCancer Biology

A. Inga

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1 paper

Recent·Most cited

Structural Basis of Mutation-Dependent p53 Tetramerization Deficiency

M. Rigoli, G. Spagnolli, G. Lorengo, P. Monti, R. Potestio, E. Biasini, A. Inga

This study investigates how mutations in p53's tetramerization domain affect its structure and function using simulations and yeast assays, showing destabilizing effects and altered transactivation.

bioRxiv · May 13, 2022Cancer Biology