Differential effects of high versus low linear energy transfer (LET) radiation on type-I interferon (IFNβ) and TREX1 responses
D. Miles, N. Cao, G. Sandison, R. D. Stewart, G. Moffitt, T. H. Pulliam, U. Parvathaneni, P. Goff, P. Nghiem, K. Stantz
This study compares the effects of high-LET fast neutrons and low-LET x-rays on IFNβ and TREX1 responses in MCC cells, finding higher RBE for IFNβ and TREX1 with neutrons.
bioRxiv · Jul 7, 2021 · PreprintCancer Biology