Topsentinol L Trisulfate, a new Marine Natural Product, that Targets Basal-like and Claudin-low Breast Cancers
N. N. El-Chaar, T. E. Smith, G. Shreshtha, S. R. Piccolo, M. K. Harper, R. M. Van Wagoner, Z. Lu, A. R. Venancio, C. M. Ireland, A. H. Bild, P. J. Moos
This study identifies topsentinol L trisulfate as a compound effective against Basal-like and Claudin-low breast cancers by inhibiting AMPK and CHK1.
bioRxiv · Apr 17, 2020Cancer Biology