An aging clock using metabolomic CSF
Nathan Hwangbo, Xinyu Zhang, Daniel Raftery, Haiwei Gu, Shu‐Ching Hu, Thomas Jude Montine, Joseph F. Quinn, Kathryn A. Chung, Amie Hiller, Dongfang Wang, Qiang Fei, Lisa Bettcher, Cyrus P. Zabetian, Elaine R. Peskind, Gail Li, , Alexander M. Franks
This paper develops a metabolomic age prediction model using CSF data from healthy humans and applies it to Alzheimer's and Parkinson's patients, finding increased prediction error in disease cohorts.
bioRxiv · Apr 4, 2021 · PreprintSystems Biology