Association between APOL1 risk variants and the occurrence of sepsis in Black patients hospitalized with infections: a retrospective cohort study
Lan Jiang, Ge Liu, Annette M. Oeser, Andrea Ihegword, Alyson L. Dickson, Laura L. Daniel, Adriana M. Hung, Nancy Jean Cox, Cecilia P. Chung, Wei‐Qi Wei, C. Michael Stein, QiPing Feng
This study investigates the association between APOL1 risk variants and sepsis occurrence in Black patients with infections, finding that the increased risk is largely due to pre-existing severe renal disease.
medRxiv · Jan 27, 2023 · PreprintGenetic & Genomic Medicine