Minimized double guide RNA libraries enable scale-limited CRISPR/Cas9 screens
Elin Madli Peets, Luca Crepaldi, Yan Zhou, Felicity R. Allen, Rasa Elmentaite, Guillaume G. Noell, Gemma Turner, Vivek Iyer, Leopold Parts
This paper introduces a minimized double guide RNA library for CRISPR/Cas9 screens, reducing scale by fivefold while maintaining performance.
bioRxiv · Nov 29, 2019 · PreprintGenetics