Machine-learning MRI stratification of genetic frontotemporal dementia for clinical trial enrichment
Mahdie Soltaninejad, Yasser Iturria‐Medina, Arabella Bouzigues, Lucy Louise Russell, Phoebe H. Foster, Eve Ferry‐Bolder, John Cornelis Van Swieten, Lize Corrine Jiskoot, Harro Seelaar, Raquel Sánchez‐Valle, Robert Jr Laforce, Caroline Graff, Daniela Galimberti, Rik R. Vandenberghe, Alexandre de Mendonça, , GENFI
This paper uses machine learning to stratify genetic frontotemporal dementia patients into subtypes and provides progression scores that improve trial enrichment efficiency.
bioRxiv · Jul 23, 2026 · PreprintNeuroscience