Author

Gerome Breen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2 Genetics· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:GWAS / association mapping· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Research Focus:software / tool· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Andrew M. McIntoshiD· 2 shared Peter HolmansiD· 2 shared Alison Foster· 1 shared Ammar Al-Chalabi· 1 shared Amy Lynham· 1 shared Anbarasu Lourdusamy· 1 shared Andrew J Pocklington· 1 shared Andrew McQuilliniD· 1 shared

Activity by Year

2015-2016 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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2 shared papersGenomics

Andrew M. McIntoshORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Common schizophrenia alleles are enriched in mutation-intolerant genes and maintained by background selection

Antonio F Pardiñas, Peter Holmans, Andrew J Pocklington, Valentina Escott-Price, Stephan Ripke, Noa Carrera, Sophie E Legge, Sophie Bishop, Darren Cameron, Marian L Hamshere, Jun Han, Leon Hubbard, Amy Lynham, Kiran Mantripragada, Elliott Rees, , James T R Walters

This study identifies 50 novel schizophrenia GWAS loci and shows common risk variants are enriched in mutation-intolerant genes maintained by background selection.

bioRxiv · Aug 9, 2016Genomics

Rare loss-of-function variants in KMT2F are associated with schizophrenia and developmental disorders

Tarjinder Singh, Mitja I. Kurki, David Curtis, Shaun M. Purcell, Lucy Crooks, Jeremy McRae, Jaana Suvisaari, Himanshu Chheda, Douglas Blackwood, Gerome Breen, Olli Pietilainen, Sebastian S. Gerety, Muhammad Ayub, Moira Blyth, Trevor Cole, , Carmel Moo

The paper identifies rare loss-of-function variants in KMT2F associated with schizophrenia and developmental disorders, showing their role in neurodevelopmental conditions.

bioRxiv · Jan 12, 2016Genomics

FORGE: multivariate calculation of gene-wide p-values from Genome-Wide Association Studies Authors and Affiliations

Inti Inal Pedroso, Michael R Barnes, Anbarasu Lourdusamy, Ammar Al-Chalabi, Gerome Breen

FORGE calculates gene-wide p-values from GWAS summary statistics, identifying additional disease genes and pathways compared to single SNP analysis.

bioRxiv · Jul 31, 2015 · PreprintGenetics