Pre-transplant TCR Network Topology Predicts Kidney Allograft Rejection Independent of HLA Mismatch
Nicholas Borcherding, Jes M. Sanders, Greg Martens, Naoka Murakami, Natnael B. Doilicho, Barbara L. Banbury, Jie He, Joseph R. Leventhal, James M. Mathew
This study uses TCR network topology from pre-transplant PBMCs to predict kidney graft rejection, achieving high accuracy independent of HLA mismatch.
bioRxiv · May 7, 2026 · PreprintImmunology