Endogenous mutational mechanisms and metabolic context shape endometrial cancer
Jian Sang, Mengyan Zhang, Sergio Chavez, Y. M. Kim, Thomas A. Veith, Weiyin Zhou, Wen Luo, Adriana Morales Miranda, Jens Luebeck, Guangyu Wang, Bin Zhu, Vineet Bafna, Stephen Jacob Chanock, Tongwu Zhang
This study identifies subtype-specific mutational mechanisms and links them to host metabolic factors in endometrial cancer using genomic and transcriptomic data from 440 tumors.
bioRxiv · Apr 7, 2026 · PreprintGenomics