Contrastive learning unites sequence and structure in a global representation of protein space
Guy Yanai, Gabriel Axel, Liam M. Longo, Nir Ben‐Tal, Rachel Kolodny
This paper introduces CLSS, a contrastive learning model that co-embeds protein sequences and structures, revealing evolutionary relationships and structural transitions.
Proceedings of the National Academy of Sciences · Aug 3, 2026Peer-reviewedBioinformatics