Author

H. Acar

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:benchmarking· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

G. Gunay· 2 shared S. Hamsici· 2 shared A. Azzawri· 1 shared B. Nami· 1 shared G. A. Lang· 1 shared M. L. Lang· 1 shared S. Kovats· 1 shared V. B. Ucar· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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2 shared papersBioengineering

G. Gunay

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Peptide aggregation-induced immunogenic cell death in a breast cancer spheroid model

H. Acar

This study demonstrates that peptide aggregation-induced immunogenic cell death (PAIIR) is more effective than traditional chemotherapeutics in stimulating ICD in breast cancer spheroids, enhancing anti-tumor immune responses.

bioRxiv · Oct 31, 2023 · PreprintBioengineering

Controllable membrane damage by tunable peptide aggregation with albumin

S. Hamsici, G. Gunay, H. Acar

This study uses engineered peptides to investigate amyloid-like aggregation mechanisms and their toxicity, showing that albumin can control aggregation and toxicity.

bioRxiv · Jun 2, 2022Bioengineering

Peptide Aggregation Induced Immunogenic Rupture (PAIIR)

G. Gunay, S. Hamsici, H. Acar, M. L. Lang, G. A. Lang, S. Kovats

This paper introduces a peptide-based tool, [II], that induces immunogenic cell death (ICD) and DAMP release to enhance antigen-specific immunity, showing improved IgG1 and IgG2a responses in influenza vaccination.

bioRxiv · Dec 11, 2021Bioengineering

Recombinant Helicobacter pylori CagA protein induces endoplasmic reticulum stress and autophagy in human cells

B. Nami, A. Azzawri, V. B. Ucar, H. Acar

This study shows that recombinant Helicobacter pylori CagA protein induces ER stress and autophagy, leading to reduced cell proliferation and increased cell death in human cells.

bioRxiv · Jun 26, 2020 · PreprintMicrobiology