Establishment and characterization of a cell line and patient-derived xenograft (PDX) from peritoneal metastasis of low-grade serous ovarian carcinoma
E. De Thaye, K. Van de Vijver, J. Van der Meulen, J. Taminau, G. Wagemans, H. Denys, J. Van Dorpe, G. Berx, W. Ceelen, J. Van Bocxlaer, O. De Wever
The paper establishes and characterizes a PDX model and cell line from peritoneal metastasis of low-grade serous ovarian carcinoma, showing sensitivity to paclitaxel and trametinib.
bioRxiv · Sep 27, 2019Cancer Biology