H. Sachdeva

Genetic load, eco-evolutionary feedback and extinction in metapopulations

The paper examines eco-evolutionary feedback in metapopulations, showing how migration thresholds affect genetic load and extinction risk under different selection regimes.

The genetic architecture of polygenic local adaptation and its role in shaping barriers to gene flow

This paper derives an expression for effective migration rate under polygenic local adaptation and shows how dominance and genetic architecture affect barriers to gene flow.

Limits to selection on standing variation in an asexual population

The paper analyzes how asexual populations respond to directional selection on standing variation, showing different variance decay rates under weak and strong selection regimes.

Reproductive isolation via polygenic local adaptation in sub-divided populations: effect of linkage disequilibria and drift

This paper investigates how polygenic local adaptation and reproductive isolation are influenced by linkage disequilibria and genetic drift in subdivided populations, showing that effective migration rates can accurately predict allele frequencies and heterozygosity.

Genetic load and extinction in peripheral populations: the roles of migration, drift and demographic stochasticity

The paper examines how migration affects genetic load and population viability in island populations, showing genetic Allee effects and critical thresholds influenced by migration rates and mutation parameters.

Polygenic local adaptation in metapopulations: a stochastic eco-evolutionary model

The paper develops a stochastic eco-evolutionary model to study local adaptation in metapopulations under hard selection, showing that polygenic traits face greater challenges in rare habitats due to migration load and demographic stochasticity.

The rates of introgression and barriers to genetic exchange between hybridizing species: sex chromosomes vs. autosomes

The paper quantitatively evaluates how sex chromosomes and autosomes act as barriers to genetic exchange between hybridizing species, showing sex chromosomes reduce introgression due to hemizygosity and reduced recombination.

Effect of partial selfing and polygenic selection on establishment in a new habitat

This paper examines how partial selfing and polygenic selection affect the establishment of a population in a new habitat through simulations and a simplified model.

Replicability of introgression under linked, polygenic selection

The paper studies how a genomic block with many weakly selected loci introgresses under directional selection and shows that growth rates depend on combined effects within a linkage scale.