H.-Y. Lai

Interactions with a phage gene underlie costs of a β-lactamase

This study identifies a phage gene, relAP1, as responsible for host-dependent fitness costs of a β-lactamase gene, blaTEM-116*, in Escherichia coli strains.

Costs of antibiotic resistance genes depend on host strain and environment and can influence community composition

This study quantifies the fitness costs of six antibiotic resistance genes across 11 Escherichia strains in two environments, showing that costs vary by host strain and environment, and can influence community composition.