Structural insight into the mechanism of neuraminidase inhibitor-resistant mutations in human-infecting H10N8 Influenza A virus
Babayemi O. Oladejo, Yuhai Bi, Christopher J. Vavricka, Chunrui Li, Yan Chai, Kun Xu, Liqiang Li, Zhe Lu, Jiandong Li, Gary Wong, Sankar Mohan, B. Mario Pinto, Haihai Jiang, Jianxun Qi, George Fu Gao, , Yan Wu
This paper identifies two drug-resistant mutations in H10N8 influenza virus and explains their structural mechanisms using crystallography, showing differences in resistance to neuraminidase inhibitors.
bioRxiv · Jul 26, 2018 · PreprintMicrobiology