Mechanism-Based Discovery of New TRIDs Targeting Ribosome Pockets
Janeena Asuma, Hanfei Wang, Saleem Y. Bhat, Huile Zhu, Hong Li, Adam A. Jabak, David M. Chenoweth, Barry S. Cooperman
This paper identifies new TRIDs that target ribosome pockets to increase PTC readthrough, showing some are more potent than ataluren in vitro.
bioRxiv · Oct 21, 2026 · PreprintBiochemistry