On improving experimental binding affinity predictions with synthetic data
Kevin Ryczko, Phyo Phyo Kyaw Zin, Jordan E. Crivelli-Decker, Punit Jha, Harish Ramadas, Lorenzo Boninsegna, Justin Overhulse, Benjamin Shields, Pablo Lemos, Sasaank Bandi, Maarten Van Damme, Amogh Sood, Lee Huntington, Mary Pitman, Martin Ganahl, , Ly Le
The paper improves binding affinity predictions by using synthetic data, showing that combining synthetic and experimental data enhances model performance.
bioRxiv · Mar 4, 2026 · PreprintMolecular Biology