Exosomes from Nef expressing monocytic cells restrict HIV-1 replication in infected cells through the assembly of stress granules
Mohammad Yunus Ansari, Hasan Imam, Nishant Kumar, Zulfazal Ahmed, Shahid Jameel
The paper shows that Nef-expressing monocytic cell exosomes inhibit HIV-1 replication by inducing stress granule assembly in infected cells, sequestering gag mRNA.
bioRxiv · Jun 11, 2017 · PreprintCell Biology