LRP2 expression in melanoma is associated with a transitory cell state, increased T cell infiltration, and is upregulated by IFNγ signaling
Martin Q. Rasmussen, Marie Louise Bønnelykke‐Behrndtz, Camilla Merrild, Ida Tvilling, Julie Nelly Christensen, Morten Milek Nielsen, Jeanette Bæhr Georgsen, Nina Naumann, Johann Mar Gudbergsson, Anders Etzerodt, Jakob Skou Pedersen, Russell William Jenkins, Søren Egedal Degn, Søren K. Moestrup, Henrik Schmidt, , Mette Marie Madsen
This study identifies LRP2 expression in melanoma as linked to a transient differentiation state, T cell infiltration, and IFNγ signaling, with associations to better prognostic features.
bioRxiv · Feb 21, 2025 · PreprintCancer Biology