Author

Hong Cui

Hospital for Sick ChildrenPrimary ORCID profile (0000-0001-5734-825X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Hong CuiiD1 paper · John Radcliffe Hospital

Biology Disciplines

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Molecular Biology· 2 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:benchmarking· 1 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:metagenomics· 1

Frequent Co-Authors

Iga KucharskaiD· 2 shared Jean‐Philippe JulieniD· 2 shared John L. RubinsteiniD· 2 shared Amy NouanesengsyiD· 1 shared Anthony Semesi· 1 shared Bebhinn TreanoriD· 1 shared Clare Burn AschneriD· 1 shared Daniel SchramekiD· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersMolecular Biology

Iga KucharskaORCID

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3 papers

Recent·Most cited

Multivalency transforms SARS-CoV-2 antibodies into broad and ultrapotent neutralizers

Edurne Rujas, Iga Kucharska, Yong Zi Tan, Samir Benlekbir, Hong Cui, Tiantian Zhao, Gregory A. Wasney, Patrick Budylowski, Furkan Guvenc, Jocelyn C. Newton, Taylor Sicard, Anthony Semesi, Krithika Muthuraman, Amy Nouanesengsy, Clare Burn Aschner, , Jean‐Philippe Julien

The paper describes a multimerization platform that transforms antibodies into potent, broad-spectrum neutralizers against SARS-CoV-2.

Nature Communications · Jun 16, 2021Peer-reviewedMolecular Biology

Identification of the C. sordellii lethal toxin receptor elucidates principles of receptor specificity in clostridial toxins

Hunsang Lee, Greg L. Beilhartz, Iga Kucharska, Swetha Raman, Hong Cui, Mandy Hiu Yi Lam, John L. Rubinstein, Daniel Schramek, Jean‐Philippe Julien, Roman A. Melnyk, Mikko Taipale

The paper identifies SEMA6A and SEMA6B as receptors for C. sordellii lethal toxin and shows how mutations can switch receptor specificity between related toxins.

bioRxiv · Dec 10, 2019 · PreprintMolecular Biology

Annotation of phenotypes using ontologies: a Gold Standard for the training and evaluation of natural language processing systems

Wasila Dahdul, Prashanti Manda, Hong Cui, James P. Balhoff, T. Alexander Dececchi, Nizar Ibrahim, Hilmar Lapp, Todd Vision, Paula M. Mabee

The paper introduces a Gold Standard corpus for ontology-based phenotype annotation and evaluates a tool's performance against human annotations.

bioRxiv · May 15, 2018Evolutionary Biology