ERK2-topoisomerase II regulatory axis is important for gene activation in immediate early genes
Heeyoun Bunch, Deukyeong Kim, Masahiro Naganuma, Reiko Nakagawa, Anh T. Q. Cong, Jaehyeon Jeong, Haruhiko Ehara, Hongha Vu, Jeong Ho Chang, Matthew J. Schellenberg, Shun‐ichi Sekine
This study identifies ERK2's role in regulating TOP2B phosphorylation to facilitate transcriptional activation of immediate early genes.
Nature Communications · Dec 14, 2023Peer-reviewedMolecular Biology