How do antimicrobial peptides interact with the outer membrane of Gram-negative bacteria? Role of lipopolysaccharides in the peptide binding, anchoring and penetration
J. C. Stephani, L. Gerhards, B. Khairalla, I. A. Solov'yov, I. Brand
This study investigates how melittin interacts with Gram-negative bacterial outer membranes, showing it anchors and translocates without disrupting membrane integrity.
bioRxiv · Aug 30, 2023Biochemistry