Three Distinct Annotation Platforms Differ in Detection of Antimicrobial Resistance Genes in Long-Read, Short-Read, and Hybrid Sequences Derived from Total Genomic DNA or from Purified Plasmid DNA
G. Maboni, R. de Paula Baptista, J. Wireman, I. Framst, A. O. Summers, S. Sanchez
This study compares three AMR gene detection platforms across different sequencing data types and DNA sources, finding that hybrid assemblies improve sensitivity and that AMR databases vary in distinguishing mobile and chromosomal resistance genes.
bioRxiv · Jul 27, 2022Microbiology