Author

I. M. Pranke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Cell Biology· 1

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Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Delaunay-Moisan· 1 shared A. Edelman· 1 shared A. Golec· 1 shared A. Hinzpeter· 1 shared A. Premchandar· 1 shared B. Chevalier· 1 shared D. A. Lomas· 1 shared D. Tondelier· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCell Biology

A. Delaunay-Moisan

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1 paper

Recent·Most cited

Keratin 8 is a scaffolding and regulatory protein of ERAD complexes

I. M. Pranke, B. Chevalier, A. Premchandar, N. Baatallah, K. F. Tomaszewski, S. Bitam, D. Tondelier, A. Golec, J. Stolk, G. L. Lukacs, P. S. Hiemstra, M. Dadlez, D. A. Lomas, J. A. Irving, A. Delaunay-Moisan, , A. Edelman

This study shows that Keratin 8 modulates ERAD complexes, enhancing degradation of misfolded proteins like Z-A1AT and F508del-CFTR, and suggests targeting K8 for therapeutic intervention in A1ATD.

bioRxiv · Feb 1, 2022Cell Biology