Evolution towards simplicity in bacterial small heat shock protein system
P. Karas, K. Kochanowicz, M. Pitek, P. Domanski, I. Obuchowski, B. Tomiczek, K. Liberek
This study shows how bacterial small heat shock proteins evolved from a two-protein system to a single-protein system with equivalent efficiency through sequence changes that alter binding properties and facilitate refolding.
bioRxiv · May 18, 2023Biochemistry