SORLA-driven endosomal trafficking regulates the oncogenic fitness of HER2
M. Pietila, P. Sahgal, E. Peuhu, N. Jantti, I. Paatero, O. M. Andersen, A. Padzik, M. Blomqvist, I. Saarinen, P. Bostrom, P. Taimen, J. Ivaska
This study shows SORLA regulates HER2 trafficking, affecting its oncogenic activity and response to therapy.
bioRxiv · Apr 11, 2018Cell Biology