Predicting Antibody Developability from Sequence using Machine Learning
Xingyao Chen, Thomas Dougherty, Chan Hong, Rachel S. Schibler, Yi Cong Zhao, Reza Sadeghi, Naim Matasci, Yi-Chieh Wu, Ian Kerman
This paper develops a machine learning pipeline to predict antibody developability from sequence, achieving high sensitivity and specificity on a dataset of 2400 antibodies.
bioRxiv · Jun 18, 2020 · PreprintBioinformatics