Engineering site-specific nucleic acid-protein conjugates by utilizing a natural RNAylation reaction
Nurseda Yilmaz Demirel, Ilayda Mumcuoglu, Gabriele Malengo, Bernd Schmeck, Anna Lena Jung, Katharina Höfer
This paper establishes RNAylation as a method to create site-specific nucleic acid-protein conjugates with improved stability and delivery capabilities in human cells.
bioRxiv · Jul 11, 2025 · PreprintBioengineering