Cigarette Smoke Extract (CSE) reduces expression of functional TRPV4 channels in primary human bronchial epithelial cells differentiated at an Air Liquid Interface (ALI) in vitro
Isabel Müller, Philipp Alt, Thomas W. Gudermann, Martina Kiefmann, Alexander Dietrich
This study shows that cigarette smoke extract reduces TRPV4 protein expression and function in human bronchial epithelial cells, potentially contributing to COPD.
Archives of Toxicology · Jun 13, 2026Peer-reviewedCell Biology