Nicotine biosynthesis completed by cryptic activating glucosylation
Benjamin T. W. Schwabe, Isabelle Angstman, Katharina Vollheyde, Zoe Ingold, Jiacheng Li, Ksenia S. Stankevich, Christopher D. Spicer, Martin A. Fascione, Gideon Grogan, Fernando Geu‐Flores, Benjamin R. Lichman
This paper reconstructs the complete nicotine biosynthesis pathway in vitro and in planta, identifying key enzymes and providing structural insights.
Nature Communications · May 18, 2026Peer-reviewedBiochemistry