Knockdown of the long non-coding RNA DNAAF3-AS1 activates the p53 pathway and remodels the H3K36me3 landscape
Anna Budkina, Anatoliy V. Zubritskiy, Daria Marakulina, Andrey Buyan, Ivan Kulakovsky, Chi Wai Yip, Jude Aneke, Jay Shin, Yulia A. Medvedeva
This study shows that knocking down DNAAF3-AS1 reduces gene-body H3K36me3, activates the p53 pathway, and alters promoter usage in apoptosis-related genes.
bioRxiv · Oct 30, 2026 · PreprintCell Biology