SREBP1 regulates mitochondrial metabolism in oncogenic KRAS expressing NSCLC
C. F. Ruiz, J. A. Haley, E. D. Montal, J. D. Haley
This study shows that SREBP1 regulates mitochondrial function, not lipogenesis, in KRAS-driven NSCLC by reducing oxidative phosphorylation and ETC subunits.
bioRxiv · Jan 15, 2020Cancer Biology