Author

J. Blesa

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Biochemistry· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Rojas-Fernandez· 1 shared C. Salinas-Rebolledo· 1 shared D. Schwefel· 1 shared G. P. Sapkota· 1 shared G. Valenzuela-Nieto· 1 shared J. A. Obeso· 1 shared J. Burkhalter· 1 shared L. F. Batiz· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Rojas-Fernandez

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1 paper

Recent·Most cited

Specific proteolysis mediated by a p97-directed proteolysis-targeting chimera (PROTAC)

C. Salinas-Rebolledo, J. Blesa, G. Valenzuela-Nieto, D. Schwefel, N. Lopez Gonzalez del Rey, M. Mendez-Ruette, J. Burkhalter, L. F. Batiz, R. Jara, J. A. Obeso, P. Chana-Cuevas, G. P. Sapkota, A. Rojas-Fernandez

This paper describes the engineering of a PROTAC that uses p97-directed proteolysis to achieve specific substrate degradation without relying on E3 ubiquitin ligases.

bioRxiv · Mar 8, 2024Biochemistry