Tissue fixation effects on human retinal lipid analysis by MALDI imaging and LC-MS/MS technologies
A. Kotnala, D. M. Anderson, N. H. Patterson, L. S. Cantrell, J. D. Messinger, C. A. Curcio, K. L. Schey
This study evaluates how tissue fixation affects lipid analysis in human retina using MALDI-IMS and LC-MS/MS, finding that fixation alters lipid signals but preserves major lipid classes.
bioRxiv · Apr 29, 2021Biochemistry