Author

J. Fuhrmann

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1

Frequent Co-Authors

A. Cano· 1 shared A.-L. Blayo· 1 shared D. Kojetin· 1 shared I. Chrisman· 1 shared J. Bass· 1 shared J. Shang· 1 shared P. Griffin· 1 shared R. Brust· 1 shared

Activity by Year

2018-2018 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Cano

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1 paper

Recent·Most cited

A structural mechanism for directing inverse agonism of PPARγ

R. Brust, J. Shang, J. Fuhrmann, J. Bass, A. Cano, Z. Heidari, I. Chrisman, A.-L. Blayo, P. Griffin, T. Kamenecka, T. Hughes, D. Kojetin

The paper shows how a phenyl-to-pyridyl substitution in PPARγ ligands converts an antagonist to an inverse agonist through a water-mediated hydrogen bond network involving Arg288.

bioRxiv · Jan 17, 2018Biochemistry