Heterogeneity in human hippocampal CaMKII transcripts reveals allosteric hub-dependent regulation
R. Sloutsky, N. Dziedzic, M. J. Dunn, R. Bates, A. P. Torres-Ocampo, S. Boopathy, B. Page, J. G. Weeks, L. H. Chao, M. M. Stratton
The paper identifies 70 CaMKII transcripts in human hippocampus and shows that the hub domain regulates kinase activity through allosteric interactions.
bioRxiv · Jan 10, 2020Biochemistry